I [27]. Ahead of the experiment, participants were verbally instructed that the experimenter
I [27]. Ahead of the experiment, participants were verbally instructed that the experimenter would draw letters on their forehead or their neck (around the back in the head below the hairline) by using a cotton bud (Fig 4A). Participants had been informed that only certainly one of these letters , b, p, q, n, v, w and o ould be drawn on their skin, and they have been instructed to report as spontaneously as possible the letter they skilled (Fig 4B). The experimenter traced the letters by PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/29046637 making use of a cotton bud inside a single continuous motion on the skin. To raise the difficulty in the activity and to not cue participants to select a technique depending on the path on the writing, all letters were drawn with the motion starting from one or the other end of every single letter, so that 
letters were traced in accordance with a canonical or noncanonical path of writing. As a result, participants initial had to create a representation of the worldwide shape in the letter before providing an answer, since the direction of the writing was uninformative. Participants had been comfortably seated on a chair and were instructed to close their eyes throughout the recording session. In 1 session, the experimenter sat in front on the participant and drew the letters on the central part of the participant’s forehead. Inside the other session, the experimenter sat in the back in the participant and drew the letters around the participant’s neck. Every single Harmine chemical information session comprised 48 trials, such as 32 presentations of ambiguous letters (eight presentations of d, b, p and q) and 6 presentations of nonambiguous letters (four presentations of n, v, w and o). Letters with their direction of drawing had been presented on a pc screen to the experimenter in a randomized order by using PsychoPy2 (v.82.0) [48]. The experimenter utilized aFig four. Strategies for the graphaesthesia activity (Experiment two). (A) The experimenter drew letters around the participants’ forehead and neck by utilizing a cotton bud whilst participants kept their eyes closed. (B) Letters included ambiguous, nonsymmetrical letters (b, d, p, q) and nonambiguous, symmetrical letters (w, n, o, v) that had been all drawn inside the canonical path of writing or in the reverse path, beginning in the opposite end on the letter. All letters have been drawn by using a single and continuous hand motion. doi:0.37journal.pone.070488.gPLOS One particular DOI:0.37journal.pone.070488 January 20,0 Anchoring the Self towards the Body in Bilateral Vestibular Losskeyboard to manually enter participants’ verbal responses, which had been saved by using PsychoPy and processed offline. Data analysis. To measure the degree of anchoring the self to the body, we calculated the proportion of ambiguous letters (d, b, p and q) that have been skilled from a firstperson perspective (e.g when participants reported the letter “q” right after the experimenter drew the letter “p” on their skin) [23]. The ability to properly represent the pattern of letters drawn on the skin was calculated because the proportion of right identification of symmetrical letters (n, v, w and o). Information had been analyzed by utilizing repeatedmeasures ANOVAs using the Web-site of stimulation (forehead vs neck) as a withinsubject element and using the Group (BVF individuals vs controls) and Gender (female vs male) as betweensubject components.ResultsAnalysis in the proportion of ambiguous letters skilled from a firstperson perspective revealed a important principal impact from the Web site of stimulation (F,42 68.96, p0.00, 2p 0.62). Fig 5 shows that letters had been more frequently knowledgeable from a very first.