Product Name: Anti-CHRNB2 antibody produced in rabbit
Synonym: Anti-Cholinergic receptor, nicotinic, β 2 (neuronal)
Product Type: Chemical
CAS NO: 579492-81-2Neuronal Signaling inhibitors
antibody Form: affinity isolated antibody
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 57 kDa
NCBI accession no.
NP_000739
Shipped in: wet ice
species reactivity
mouse, zebrafish, canine, bovine, human, pig
Storage temp.: −20°C
Application: Anti-CHRNB2 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.
Biochem/physiol Actions:
CHRNB2 is a transmembrane, oligomeric, ligand-gated nicotinic receptor that induces ion channel opening for the movement of positive ions when it is activated by cholinergic binding. Nicotinic acetylcholine receptors mediate presynaptic, postsynaptic and extrasynaptic signaling. Mutations in gene that codes for CHRNB2 have been observed in autosomal dominant nocturnal frontal lobe epilepsy and memory deficits.
Immunogen:
The immunogen for anti-CHRNB2 antibody: synthetic peptide derected towards the N terminal of human CHRNB2
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: SGVWGTDTEERLVEHLLDPSRYNKL
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/329/1/175