Product Name: Anti-CCL7 antibody produced in rabbit
Synonym: Anti-Chemokine (C-C motif) ligand 7
Product Type: Chemical
CAS NO: 1393124-08-7Integrin inhibitors
antibody Form: affinity isolated antibody
application(s)
immunohistochemistry: suitable
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 9 kDa
NCBI accession no.
NP_006264
Shipped in: wet ice
species reactivity
human, pig, horse
Storage temp.: −20°C
Antigen Background:
CCL7, also known as MCP3, is a CC chemokine that binds monocytes and has been shown to regulate macrophage activity.
Application: Anti-CCL7 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.
Biochem/physiol Actions:
CCL7 exhibits a chemotactic activity for most leukocytes, monocytes and T cells. It functions by binding to various chemokine receptors such as CCR1, CCR2, CCR3 and CCR5. CCL7 is implicated in chronic inflammatory diseases such as asthma, ulcerative colitis and bilial cirrhosis.
Immunogen:
The immunogen for anti-CCL7 antibody: synthetic peptide derected towards the N terminal of human CCL7
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: TSTTCCYRFINKKIPKQRLESYRRT
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/328/1/141