Product Name: Anti-E2F1 (AB1) antibody produced in rabbit
Synonym: Anti-E2F transcription factor 1
Product Type: Chemical
CAS NO: 146669-29-6Polo-like Kinase (PLK) inhibitors
antibody Form: affinity isolated antibody
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 47 kDa
NCBI accession no.
NP_005216
Shipped in: wet ice
species reactivity
guinea pig, mouse, rat, canine, human, horse, rabbit
Storage temp.: −20°C
Application: Anti-E2F1 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml.
Biochem/physiol Actions:
E2F1 displays both tumor promoting and tumor suppressor activities. It acts along with p53 to prevent tumorigenesis and oncogenic transFormation. The crosstalk between E2F1 and c-myc control cell signaling, transcription, proliferation and apoptosis.
General description: The members of E2F family of transcription factors bind to promoter regions and regulate cell proliferation.
Immunogen:
The immunogen for anti-E2F1 antibody: synthetic peptide derected towards the C terminal of human E2F1
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: REDFSGLLPEEFISLSPPHEALDYH
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/327/3/982