Product Name: Anti-TNFRSF18 antibody produced in rabbit
Synonym: Anti-Tumor necrosis factor receptor superfamily, member 18
Product Type: Chemical
CAS NO: 120638-55-3Antifolate inhibitors
antibody Form: affinity isolated antibody
application(s)
immunohistochemistry: suitable
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 26 kDa
NCBI accession no.
NP_004186
Shipped in: wet ice
species reactivity
human
Storage temp.: −20°C
Application: Anti-TNFRSF18 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 2-4 μg/ml is suitable.
Biochem/physiol Actions:
TNFRSF18 regulates cell death mediated by T cell receptors. It has important role in inflammatory responses that are involved in autoimmune disorders such as collagen-induced arthritis, experimental autoimmune encephalomyelitis and autoimmune gastritis.
General description: TNFRSF18 belongs to TNF receptor super family. It is a 228-amino acid type 1 transmembrane protein with a cysteine-rich extracellular domain.
Immunogen:
The immunogen for anti-TNFRSF18 antibody: synthetic peptide derected towards the C terminal of human TNFRSF18
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: LRSQCMWPRETQLLLEVPPSTEDAR
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/327/3/770