Product Name :
Rabbit anti-TP53BP1 Polyclonal Antibody
Synonym :
53BP1; p202; p53BP1; TDRD30; TP53
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200IF 1:50 – 1:200
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1763-1977 of human TP53BP1 (NP_001135452.1).
Concentration :
Purification :
Affinity purification
Clonality:
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
TP53BP1 (tumor protein p53 binding protein 1) is a protein-coding gene. Go annotations related to this gene include methylated histone residue binding and p53 binding.Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis.Enhances TP53-mediated transcriptional activation.
UniProt :
Q12888
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym 53BP1; p202; p53BP1; TDRD30; TP53 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:200IF 1:50 – 1:200 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1763-1977 of human TP53BP1 (NP_001135452.1). |Positive control A-431 |Properties |Purification Affinity purification |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background TP53BP1 (tumor protein p53 binding protein 1) is a protein-coding gene. Go annotations related to this gene include methylated histone residue binding and p53 binding.Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis.Enhances TP53-mediated transcriptional activation. |Cellular localization Chromosome,Nucleus,centromere,kinetochore |UniProt Q12888 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-TP53BP1 Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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