Name :
Recombinant Human PLGF/PGF Protein (mFc Tag)
Biological Activity :
Background :
Biological Activity :
1. Immobilized human PGF-mFc at 10 μg/mL (100 μL/well) can bind human VEGFR1-His (Cat:10136-H08H). The EC50 of human VEGFR1-His (Cat:10136-H08H) is 0.19-0.43 μg/mL.2. Labeled biotin to PLGF / PGF Protein, Human, Recombinant (Fc Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of PLGF / PGF Protein, Human, Recombinant (Fc Tag), Biotinylated (Cat. 10274-H05H-B) bound to Conbercept was 4.5 nM.
Expression Host :
Human
Source :
HEK293 Cells
Tag :
Protein Accession No. :
NP_002623.2
NCBI Gene ID :
Synonyms :
Synonyms :
placental growth factor
Amino Acid Sequence :
Molecular Weight :
The recombinant human PGF consists 386 amino acids and predicts a molecular mass of 43.7 kDa.
Purity :
> 95 % as determined by SDS-PAGE.
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg protein as determined by the LAL method.
Protein Construction :
A DNA sequence encoding the human PGF (NP_002623.2) (Met1-Arg170) was expressed with the Fc region of mouse IgG1 at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
D12S1900 Protein, Human; PGFL Protein, Human; PLGF Protein, Human; PlGF-2 Protein, Human; SHGC-10760 Protein, Human PLGF/PGF 背景信息
References & Citations :
Nagy JA, et al. (2003) VEGF-A(164/165) and PLGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med. 13(5): 169-75.Chaballe L, et al. (2011) Placental growth factor: a tissue modelling factor with therapeutic potentials in neurology? Acta Neurol Belg. 111(1): 10-7.Odorisio T, et al. (2006) The placental growth factor in skin angiogenesis. J Dermatol Sci. 41(1): 11-9.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
IL-11 Proteinsite
Carbonic Anhydrase VIII/CA8 ProteinSpecies
Popular categories:
Ubiquitin-Specific Peptidase 30
HB-EGF