Product Name :
Tetrazine-SS-Biotin
Tag:
CAS :
Chemical Formula:
C24H32N8O3S3
Molecular Weight :
576.77
Physical Form:
red oil
Solubility :
DCM, acetonitrile, DMF and DMSO
Storage at:
Additional information :
Specifications:|Chemical Formula: C24H32N8O3S3|Molecular Weight: 576.77|CAS: N/A|Purity: >90%|Physical Form: red oil|Solubility: DCM, acetonitrile, DMF and DMSO|Storage at: -20 oC|Tetrazine-SS-Biotin is a cleavable biotinylation reagent containing a tetrazine moiety for inverse electron demand Diels-Alder cycloaddition reactions. The tetrazine will react with strained alkenes such as trans-cyclooctene, norbornene and cyclopropene to yield a stable dihydropyridazine linkage. The integral disulfide bond enables the release of the biotin group from the labeled molecule using DTT or other reducing agents|Biocompatible – click reaction occurs efficiently under mild buffer conditions; requires no accessory reagents such as a copper catalyst or reducing agents (e.2589531-76-8 web g.49763-96-4 custom synthesis DTT)|Chemoselective – tetrazines and trans-cyclooctene groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency|Unprecedented kinetics – inverse-electron demand Diels-Alder chemistry is the fastest bioorthogonal ligation available|Cleavable SS bond – can be cleaved with DTT, GSH or TCEP