Product Name :
MK-3697
Description:
MK-3697 is a highly potent, orally bioavailable selective orexin 2 receptor antagonists . MK-3697 is also the third insomnia drug, currently being developed by Merck. MK-3697 has Ki = 0.95 nM. Orexin receptor antagonists have demonstrated clinical utility for the treatment of insomnia. In vivo tests results on MK-3697 demonstrated improved stability and TDI profiles as well as excellent sleep efficacy across species.
CAS:
1224846-01-8
Molecular Weight:
447.51
Formula:
C23H21N5O3S
Chemical Name:
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5′-methyl-5-(1,3-thiazol-2-yl)-[2,3′-bipyridine]-4-carboxamide
Smiles :
CC1C=C(C=NC=1)C1=CC(C(=O)NCC2=CC=C(OC)C(=N2)OC)=C(C=N1)C1=NC=CS1
InChiKey:
VSOUDUXMPUHJEU-UHFFFAOYSA-N
InChi :
InChI=1S/C23H21N5O3S/c1-14-8-15(11-24-10-14)19-9-17(18(13-26-19)23-25-6-7-32-23)21(29)27-12-16-4-5-20(30-2)22(28-16)31-3/h4-11,13H,12H2,1-3H3,(H,27,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
MK-3697 is a highly potent, orally bioavailable selective orexin 2 receptor antagonists . MK-3697 is also the third insomnia drug, currently being developed by Merck. MK-3697 has Ki = 0.95 nM. Orexin receptor antagonists have demonstrated clinical utility for the treatment of insomnia.Edoxaban Autophagy In vivo tests results on MK-3697 demonstrated improved stability and TDI profiles as well as excellent sleep efficacy across species.MOG peptide (35-55) Cancer |Product information|CAS Number: 1224846-01-8|Molecular Weight: 447.PMID:32491486 51|Formula: C23H21N5O3S|Synonym:|MK 3697|MK3697|Chemical Name: N-[(5,6-dimethoxypyridin-2-yl)methyl]-5′-methyl-5-(1,3-thiazol-2-yl)-[2,3′-bipyridine]-4-carboxamide|Smiles: CC1C=C(C=NC=1)C1=CC(C(=O)NCC2=CC=C(OC)C(=N2)OC)=C(C=N1)C1=NC=CS1|InChiKey: VSOUDUXMPUHJEU-UHFFFAOYSA-N|InChi: InChI=1S/C23H21N5O3S/c1-14-8-15(11-24-10-14)19-9-17(18(13-26-19)23-25-6-7-32-23)21(29)27-12-16-4-5-20(30-2)22(28-16)31-3/h4-11,13H,12H2,1-3H3,(H,27,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|