Name :
Recombinant Human Neurotensin Protein (hFc Tag)
Biological Activity :
Background :
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs to the neurotensin family. NTS is an endogenous tridecapeptide of the central nervous system and the gastrointestinal tract of different mammalian species including the human. The human gene encoding neurotensin has previously been assigned to chromosome 12 but no regional localization was available. NTS is widely expressed in the central and peripheral nervous system, which is mainly mediated by neurotensin receptor1 (NTSR1) to activate the related downstream signaling pathways. Diseases associated with NTS include Dumping Syndrome and Duodenogastric Reflux.
Biological Activity :
Testing in progress
Expression Host :
Human
Source :
HEK293 Cells
Tag :
Protein Accession No. :
NP_006174.1
NCBI Gene ID :
Synonyms :
Synonyms :
neurotensin
Amino Acid Sequence :
Molecular Weight :
The recombinant human NTS consists 363 amino acids and predicts a molecular mass of 41 kDa.
Purity :
> 85 % as determined by SDS-PAGE.
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg protein as determined by the LAL method.
Protein Construction :
A DNA sequence encoding the human NTS (NP_006174.1) (Met1-Leu148) was expressed with the Fc region of human IgG1 at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
NMN-125 Protein, Human; NN Protein, Human; NT Protein, Human; NT/N Protein, Human; NTS1 Protein, Human Neurotensin 背景信息 NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs to the neurotensin family. NTS is an endogenous tridecapeptide of the central nervous system and the gastrointestinal tract of different mammalian species including the human. The human gene encoding neurotensin has previously been assigned to chromosome 12 but no regional localization was available. NTS is widely expressed in the central and peripheral nervous system, which is mainly mediated by neurotensin receptor1 (NTSR1) to activate the related downstream signaling pathways. Diseases associated with NTS include Dumping Syndrome and Duodenogastric Reflux.
References & Citations :
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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