Name :
Recombinant Human INSL6 Protein (His Tag)
Biological Activity :
Background :
INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the Insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified Insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features.
Biological Activity :
Testing in progress
Expression Host :
Human
Source :
HEK293 Cells
Tag :
Protein Accession No. :
NP_009110.2
NCBI Gene ID :
Synonyms :
Synonyms :
Insulin-like 6
Amino Acid Sequence :
Molecular Weight :
The recombinant human INSL6 consists of 189 amino acids and predicts a molecular mass of 22.1 kDa.
Purity :
> 90 % as determined by SDS-PAGE.
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg protein as determined by the LAL method.
Protein Construction :
A DNA sequence encoding the human INSL6 (NP_009110.2) (Met1-Phe198) was expressed with a polyhistidine tag at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
RIF1 Protein, Human INSL6 背景信息 INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the Insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified Insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features.
References & Citations :
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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