Name :
Recombinant Human Galectin-8/LGALS8 Protein (GST Tag)
Biological Activity :
Background :
Biological Activity :
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 0.2-1 μg/ml.
Expression Host :
Human
Source :
E. coli
Tag :
Protein Accession No. :
AAF19370.1
NCBI Gene ID :
Synonyms :
Synonyms :
lectin, galactoside-binding, soluble, 8
Amino Acid Sequence :
Molecular Weight :
The recombinant human LGALS8/GST chimera consists of 550 amino acids and predicts a molecular mass of 62.7 kDa. The apparent molecular mass of rh LGALS8/GST is approximately 60 kDa in SDS-PAGE under reducing conditions.
Purity :
> 70 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
Please contact us for more information.
Protein Construction :
A DNA sequence encoding human LGALS8 (AAF19370.1) (Met 1-Trp 317) was fused with the GST tag at the N-terminus.
Buffer Solution :
Lyophilized from sterile 50mM Tris, 0.1 M NaCl, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
Gal-8 Protein, Human; PCTA-1 Protein, Human; PCTA1 Protein, Human; Po66-CBP Protein, Human Galectin-8/LGALS8 背景信息
References & Citations :
Levy Y, et al. (2003) Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin. J Biol Chem. 278(16):14533-42.Nishi N, et al. (2003) Galectin-8 modulates neutrophil function via interaction with integrin alphaM. Glycobiology. 13(11):755-63.Bidon-Wagner N, et al. (2004) Human galectin-8 isoforms and cancer. Glycoconj J. 19(7-9):557-63.
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