Name :
Recombinant Human Alkaline Phosphatase/PLAP/ALPP Protein (His Tag)
Biological Activity :
Background :
Most importantly, placental Alkaline Phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental Alkaline Phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
Biological Activity :
Testing in progress
Expression Host :
Human
Source :
Yeast
Tag :
Protein Accession No. :
AAH09647.1
NCBI Gene ID :
Synonyms :
Synonyms :
Alkaline Phosphatase, placental
Amino Acid Sequence :
Molecular Weight :
The recombinant human ALPP consists of 494 amino acids and predicts a molecular mass of 54.1 KDa. It migrates as an approximately 66 KDa band in SDS-PAGE under reducing conditions.
Purity :
> 80 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
Please contact us for more information.
Protein Construction :
A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus.
Buffer Solution :
Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20 % glycerol, pH 7.5.Please contact us for any concerns or special requirements.Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
Liquid. It is shipped out with blue ice.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
ALP Protein, Human; ALPI Protein, Human; IAP Protein, Human; PALP Protein, Human; PLAP Protein, Human; PLAP-1 Protein, Human Alkaline Phosphatase/PLAP/ALPP 背景信息 Most importantly, placental Alkaline Phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental Alkaline Phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
References & Citations :
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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