Ficantly enhanced at Braak stage III/IV. By contrast, pSer396 tau and pSer262 tau are only weakly expressed in all analyzed brain regions and only minor progression was observed. When comparing…
L nucleolar ribonucleoprotein complicated mTOR Signaling Pathway Pink/Parkin Mediated Mitophagy mitochondrial electron transfer flavoprotein complicated DNA Damage/Telomere Anxiety Induced Senescence p-value adj.p-value three.79E-04 3.91E-02 1.85E-02 1.93E-02 8.40E-03 two.30E-03 3.70E-02 8.40E-03…
Min as pretreatment. Sections were also examined microscopically for the look, severity and topographical distribution of immunostaining of A inside brain parenchyma (as amyloid plaques) and cerebral vessels (as CAA).…
Ions. Each tab in the file consists of gene sets of a certain Recombinant?Proteins Esterase D/FGH Protein library that was located to be enriched within the module. The first column…
Ctors) normalized for the quantity of special hits of the respective sequencing run when mapped for the genome. The upper-limit cut-offs shown in the supplementary material were calculated as described…
Olumn shows the ratio of overlapping module genes with the gene set (Overlap), the following 4 columns are connected to statistics (P-value, Adjusted P-value, Z-score, Combined Score) plus the fifth…
Th haematoxylin. Hereafter, slides were dehydrated and mounted making use of the non-aqueous mounting medium Quick-D (Klinipath, Duiven, The Netherlands). Damaging controls have been obtained by performing the exact same…
Th WT and ASO mice (Extra files four and 5). This Clusterin/APOJ Protein Human module is diverse but is enriched in terms connected to G-protein coupled receptor signaling (GO:0007186), oxidoreductase…
Nal cord of mice transgenic for full-length human P301S Tau as a function of time. Insets depict the framed locations at higher magnification. Note the absence of AT100 immunoreactivity in…
Yakrishna Ambati4,5, Krzysztof Zablocki3, Elisabetta Gazzerro2, Stephen Arkle1, Claudio Bruno2 and Dariusz C. G ecki1*AbstractDuchenne muscular dystrophy (DMD) would be the most common inherited muscle disorder that causes severe disability…