Product Name: Anti-IKBKG antibody produced in rabbit
Synonym: Anti-Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase γ
Product Type: Chemical
CAS NO: 1474110-21-8Porcupine inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 48 kDa
NCBI accession no.
NP_001093326
Shipped in: wet ice
species reactivity
bovine, rat, rabbit, guinea pig, human, canine, mouse, horse
Storage temp.: −20°C
Application: Anti-IKBKG antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
Biochem/physiol Actions:
The Inhibitor of nuclear factor-κB (IκB) kinase (IKK) complex is a central regulator of NF-κB signaling and activation of target genes. The IKK complex is made up of IKK1, IKK2 and NEMO or IKK γ. Two subunits of NEMO bind the IKK1-IKK2 heterodimer to make up the IKK complex. IKK γ lacks a catalytic domain but has regulatory function on the IKK complex.
Immunogen:
The immunogen for anti-IKBKG antibody: synthetic peptide derected towards the middle region of human IKBKG
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: LGELQESQSRLEAATKECQALEGRA
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/329/2/403.3