Product Name: Anti-HSP90AB1 antibody produced in rabbit
Synonym: Anti-Heat shock protein 90 kDa α (cytosolic), class B member 1
Product Type: Chemical
CAS NO: 1801747-42-15-HT Receptor inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Mol wt: mol wt 83 kDa
NCBI accession no.
NP_031381
packaging
pkg of 100 μg lyophilized powder
pkg of 100 μL buffered aqueous solution
species reactivity
human, goat, mouse, bovine, canine, guinea pig
Storage temp.: −20°C
Application: Anti- HSP90AB1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.625 μg/ml.
Biochem/physiol Actions:
HSP90AB1 (heat shock protein 90kDa α (cytosolic), class B member 1) is a molecular chaperone that mediates protein folding and intracellular trafficking. It interacts with important oncoproteins such as MET, Akt, p53 and Raf-1 kinase and modulates the signaling pathway that results in cell proliferation and survival.
Immunogen:
The immunogen for anti-HSP90AB1 antibody: synthetic peptide derected towards the N terminal of human HSP90AB1
Sequence:
Synthetic peptide located within the following region: MPEEVHHGEEEVETFAFQAEIAQLM
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/328/1/2.2