Product Name: Anti-APPD antibody produced in rabbit
Product Type: Chemical
CAS NO: 309913-83-5Endothelin Receptor inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 31 kDa
NCBI accession no.
NP_077286
Shipped in: wet ice
species reactivity
canine, human, mouse, rat, bovine, yeast
Storage temp.: −20°C
Application: Anti-APPD antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.
Biochem/physiol Actions:
APPD (PLEKHF1) is Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains. It induces apoptosis by activating lysosomal-mitochondrial pathway resulting in permeabilization of lysosomal membrane and alteration of mitochondrial membrane potential.
Immunogen:
The immunogen for anti-APPD antibody: synthetic peptide derected towards the C terminal of human APPD
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: QPAHLARPICGASSGDDDDSDEDKE
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/328/1/284