For occasion, the PI3 kinase pathway can be activated by the insulin-receptor substrate (IRS), a key substrate of the IGF-IR. This activation qualified prospects to even further phosphorylation and activation of PKB/Akt kinase
These final results suggest that the suppressive influence of lentinan on epithelial TNFR1 expression soon after the receptor endocytosis could be just one of the essential mechanisms for its anti-inflammatory…